Publications
A three-dimensional computational analysis of magnetic resonance images characterizes the biological aggressiveness in malignant brain tumors
J. Pérez-Beteta, A. Martínez-González, V. M. Pérez-García
Journal of the Royal Society Interface
A transient population precedes and supports the acquisition of temozolomide resistance in glioblastoma
M. Rabe, S. Dummont, A. Álvarez-Arenas Alcami, H. Janati, J. Belmonte-Beitia, G. F. Calvo, C. Thibault-Charpentier, Q. Séry, C. Chauvin, N. Joalland, F. Briand, E. Scotet, C. Pecqueur, J. Clairambault, L. Oliver, A. Nadaradjane, V. M. Pérez-García, P. François Cartron, C. Gratas, F. M. Vallette
Cancer Research (submitted)
Approaching the Rank Aggregation Problem by Local Search-based Metaheuristics.
J. A. Aledo, J. A. Gámez, D. Molina.
Information Sciences (2018)
Changes in the retreatment radiation tolerance of the spinal cord with time after the initial treatment
T. E. Wooley, J. Belmonte-Beitia, G. F. Calvo, J. W. Hopewell, E. A. Gaffney and B. Jones
International Journal of Radiation Biology 94:6, 515-531 (2018)
Dynamics of Darwinian Selection, Lamarckian Induction and Microvesicle Transfer: Role on Drug Resistance in Cancer
A. Alvarez-Arenas, A. Podolski-Renic, J. Belmonte-Beitia, M. Pesic, G. F. Calvo
Scientific Reports (Submitted)
Flux density and coating strongly influence nanoparticle internalization into cells
B. Cortés-Llanos, G. F. Calvo, J. Belmonte-Beitia, S. M. Ocampo, L. de la Cueva, L. Pérez, C. Belda-Iniesta, G. Salas and A. Ayuso-Sacido.
Nanoletters (submitted)
Global heterogeneity assessed with 18F-FDG PET/CT. Relation with biological variables and prognosis in locally advanced breast cancer.
M. J. Tello-Galán, A. M. García Vicente, J. Pérez-Beteta, M. Amo-Salas, G. A. Jiménez Londoño, F. J. Pena Pardo, A. Soriano, V. M. Pérez García
Annals of Nuclear Medicine (submitted)
Intratumoral heterogeneity in 18F-FDG PET/CT by textural analysis in breast cancer as predictive and prognostic subrogate.
D. Molina A. M. García Vicente, J. Pérez-Beteta, M. Amo-Salas, A. Martínez-González, M. J. Tello Galán, A. Soriano, V. M. Pérez-García
Annals of Nuclear Medicine 32(6), 379-388 (2018).
Is it possible to establish the postoperative extent of resection of glioblastoma with 18F-fluorocholine PET/CT?
A. M. García Vicente, J. Pérez-Beteta, M. Calvo, M. Villena, A. Soriano
Clinical Nuclear Medicine 43(8) e269-e273 (2018).
Labile Hemoglobin as a Glycemic Biomarker for Patient-Specific Monitoring of Diabetes: Mathematical Modelling Approach
O. León-Triana, G. F. Calvo, J. Belmonte-Beitia, M. Rosa Durán, J. Escribano-Serrano, A. Michan-Doña, V. M. Pérez-García
Journal of the Royal Society Interface, 15(142), 20180224 (2018)
Modulation of antioxidant potential with coenzyme Q10 suppressed invasion of temozolomide resistant rat glioma in vitro and in vivo
S. Stojkovic, A. Podolski-Renic, J. Dinic, T. Stankovic, M. Jovanovic, S. Hadžic, J.M. Ayuso, M. Virumbrales-Muñoz, L. J. Fernández, I. Ochoa, V.M. Perez-Garcia, M. Pešic
Oxidative Medicine and Cellular Longevity (submitted)
Morphological features on MR images classify multiple glioblastomas into two prognostic groups
J. Pérez-Beteta, D. Molina, M. Villena, M. Rodríguez, C. Velásquez, J. Martino, B. Meléndez, A.R. de Lope, R. Morcillo, J. Sepúlveda, A. Hernández, A. Ramos, J. Barcia, P. Lara, D. Albillo, A. Revert, E. Arana, V.M. Pérez-Garcia
American Journal of Neuro-radiology (submitted)
Morphological MRI-based features provide pretreatment and post-surgery survival prediction in glioblastoma
J. Pérez-Beteta, D. Molina-García, A. Martínez-González, M. Amo, A. Henares-Molina, B. Luque, E. Arregui, M. Calvo, J.M.Borrás, J. Martino, C. Velasquez, B. Meléndez, A. R. de Lope, R. Moreno, J. A. Barcia, B. Asenjo, M. Benavides, I. Herruzo, P. C. Lara, R. Cabrera, D. Albillo, M. Navarro, L. A. Pérez-Romasanta, A. Revert, E. Arana, V. M. Pérez-García
European Radiology (2018) doi:10.1007/s00330-018-5758-7
Optimal control problems for differential equations applied to tumor growth: state of the art.
C. Rojas, J. Belmonte-Beitia
Applied Mathematics and Nonlinear Sciences, 3(2), 15-41, (2018)
Regulation of the oxidative balance with Coenzyme Q10 sensitizes human glioblastoma cells to radiation and temozolomide
J. Frontiñán, R. Santiago, C. Nieva, G. Ferrín, A. Martínez, M.V. Gomez, M. Moreno, J. Ariza, E. Lozano, J. Arjona, A. Gil, M. De la Mata, M. Pesic, JR Peinado, JM Villalba, L. Pérez-Romasanta, V. M. Pérez-García, F. J. Alcaín, M. Durán-Prado
Radiotherapy and Oncology 128(2) 236-244 (2018)
Survival prediction in Glioblastoma: Man versus Machine
D. Molina-García, L. Vera, J. Pérez-Beteta, E. Arana, V. M. Pérez-García
Scientific Reports (submitted)
Symmetry analysis for a Fisher equation with exponential diffusion
M.L. Gandarias, M. Rosa, R. Tracina
Mathematical Methods in the Applied Sciences (2018)
Towards Uncertainty-Assisted Brain Tumor Segmentation and Survival Prediction
A. Jungo, R. McKinley, R. Meier, U. Knecht, L. Vera, J. Pérez-Beteta, D. Molina, V. M. Pérez-García, R. Wiest, M. Reyes
In: Brainlesion: Glioma, Multiple Sclerosis, Stroke and Traumatic Brain Injuries. BrainLes 2017. Lecture Notes in Computer Science, vol 10670. Springer
Tumor Surface Regularity at MR Imaging Predicts Survival and Response to Surgery in Patients with Glioblastoma
J. Pérez-Beteta, D. Molina, A. Fernández, B. Luque, E. Arregui, M. Calvo, J. M. Borrás, A. Fernández-Romero, B. Luque, B. Meléndez, A.R. de Lope, R. Moreno, L. Iglesias, J.A. Barcia, J. Martino, C. Velasquez, B. Asenjo, M. Benavides, I. Herruzo, A. Revert, E. Arana, V. M. Pérez-García
Radiology 288(1), 218-225 (2018)
Ultimate dynamics and optimal control of a multi-compartment model of tumor resistance to chemotherapy
A. Alvarez-Arenas, K.E. Starkov, G. F. Calvo, Juan Belmonte-Beitia
Discrete and Continuous Dynamical Systems B (submitted)
A Mathematical Model Describes the Malignant Transformation of Low Grade Gliomas: Prognostic implications
M. U. Bogdanska, M. Bodnar, M. J. Piotrowska, M. Murek, P. Schucht, J. Beck, A. Martínez-González, V. M. Pérez-García
PLOS One 12(8):e0179999 (2017)
A mathematical model of low grade gliomas treated with temozolomide and its therapeutical implications
M. U. Bogdanska, M. Bodnar, J. Belmonte-Beitia, M. Murek, P. Schucht, J. Beck, V.M. Pérez-García
Mathematical Biosciences 288 (2017) 1-13
Assessing response in locally advanced breast cancer treated with neaodjuvant chemotherapy: Predictive and prognostic potential of volume-based metabolic variables with 18F-FDG PET/CT
M.D.M. Munoz-Sanchez, M. Soriano, A. M. Garcia-Vicente, M. J. Molina-Garrido, J. Perez-Beteta, A. Olaverri-Herandez, D. Molina-Garcia, J. A. S. Crespo, V. M. Perez-Garcia, E. Val-Pérez, F. Martín-Ordóñez, JI Chacón-Muñiz, R Álvarez-Cabellos, R Espinosa-Aunión, C. Ortega-Ruipérez, M.J. Cantero, A. Castro, E. Vaquero, E. Catalá, F. Torrecillas and A. Soriano-Castrejón
Cancer Research 77, P4-01-04 (2017)
Combined in-silico and on-chip validation of pseudopalisade formation hypothesis in Glioblastoma
A. Martínez-González, J. M. Ayuso, R. Monge, M. Virumbrales-Muñoz, G. A. Llamazares, A. Hernández-Laín, P. Sánchez-Gómez, V. M. Pérez-García, L. J. Fernández, I. Ochoa
Neuro-Oncology 19(3):iii62-iii62 (2017)
Glioblastoma on a microfluidic chip: Generating pseudopalisades and enhancing cancer cell’s aggressiveness through blood vessel obstruction events
J.M. Ayuso, R. Monge, A. Martínez-González, G.A. Llamazares, J. Berganzo, A. Hernández-Laín, J. Santolaria, M. Doblaré, C. Hubert, J. Rich, P. Sánchez-Gómez, V.M. Pérez-García, I. Ochoa, L.J. Fernández
Neuro-Oncology 19(4), 503-513 (2017).
Glioblastoma: Does the pre-treatment geometry matter? A postcontrast T1 MRI-based study
J. Pérez-Beteta, A. Martínez-González, D. Molina, M. Amo, B. Luque, E. Arregui, M. Calvo, J. M. Borrás, C. López, M. Claramonte, J. Barcia, L. Iglesias, J. Avecillas, D.Albillo, M. Navarro, J.M. Villanueva, J.C. Paniagua, J. Martino, C. Velasquez, B. Asenjo, M. Benavides, I. Herruzo, M.C. Delgado, A. Del Valle, A. Falkov, P. Schucht, E. Arana, L. Pérez-Romasanta, V. M.Pérez-García
European Radiology 27(3), 1096-1104 (2017)
Hyperspectral imaging for brain tumour identification and boundaries delineation in real-time during neurosurgical operations
J. F. Piñeiro, D. Bulters, S. Ortega, H. Fabelo, S. Kabwama, C. Sosa, S. Bishop, A. Martínez-González, A. Szolna, G. M. Callico
Neuro Oncol (2017) 19 (suppl_3): iii44.
Lack of robustness of textural measures obtained from 3D brain tumor MRIs impose a need for standardization
D. Molina, J. Pérez-Beteta, A. Martínez-González, J. Martino, C. Velasquez, E. Arana, V. M. Pérez-García
PLoS One 12(6):e0178843 (2017)
Malignant transformation of low-grade gliomas. Prognostic implications from mathematical model
M. U. Bogdanska, M. Bodnar, M. J. Piotrowska, M. Murek, P. Schucht, J. Beck, A. Martínez-Gonzalez, V. M. Perez-Garcia
Neuro-Oncology 19(3), iii85-iii85 (2017)
Metabolic tumor burden assessed by dual time point 18F-FDG PET/CT in locally advanced breast cancer: Relation with tumor biology.
A. M. García-Vicente, J. Pérez-Beteta, A. Martínez-González, V.M. Pérez-García, D. Molina, G.A. Jiménez Londoño, A. Soriano
Molecular Imaging and Biology 19(4), 636-644 (2017)
Non-Standard Radiotherapy Fractionations Delay the Time to Malignant Transformation in Low-Grade Gliomas
A. Henares-Molina, S. Benzekry, P. C. Lara, M. García-Rojo, V. M Pérez-García, A. Martínez-González
PLoS One 12(6):e0178552 (2017)
Novel geometrical imaging biomarkers predict survival and allow for patient selection for surgery in glioblastoma patients
J. Pérez-Beteta, D. Molina, A. Martínez-González, E. Arregui, B. Asenjo, L. Iglesias, J. Martino, L. Pérez-Romasanta, E. Arana, V. M. Pérez-García
Neuro-Oncology 19(3):iii80-iii80 (2017)
Optimized radiotherapy protocols delay the malignant transformation of low-grade gliomas in-silico
A. Henares-Molina, S. Benzecry, P. Lara, M. García-Rojo, V. M. Pérez-García, A. Martínez-González
Neuro Oncol (2017) 19 (3): iii12.
Optimizing the delivery of combination therapy for tumors: A mathematical model
C. Rojas Rodríguez and J. Belmonte-Beitia
International Journal of Biomathematics 10 (2017) 1750039
Predictive and prognostic potential of volume-based metabolic variables obtained by basal 18F-FDG PET/CT in breast cancer with neoadjuvant chemotherapy indication
A. M. García Vicente, J. Pérez-Beteta, M. Amo-Salas, D. Molina, G. Jiménez Londoño, A. M. Soriano, M. J. Tello, F. J. Pena Pardo, A. Martínez-González
Revista Española de Medicina Nuclear e Imagen Molecular 37(2), 73-79 (2017)
Recommendations for computation of textural measures obtained from 3D brain tumor MRIs: A robustness analysis points out the need for standardization
D. Molina, J. Pérez-Beteta, A. Martínez-González, C. Velásquez, J. Martino, B. Luque, A. Revert, I. Herruzo, E. Arana, V. M. Pérez-García
Neuro-Oncology 19 (3): iii44 (2017)
Stochastic modelling of slow-progressing tumors: analysis and applications to the cell interplay and control of low grade gliomas
C. Rojas-Rodríguez, G. Fernández Calvo, I. Ramis-Conde, J. Belmonte-Beitia
Communications in Nonlinear Science and Numerical Simulation 49 (2017) 63-80
Tackling the supervised label ranking problem by bagging weak learners
J. A. Aledo, J. A. Gámez, D. Molina
Information Fusion 35, 38-50 (2017)
Textural features and SUV-based variables assessed by dual time point 18F-FDG PET/CT in locally advanced breast cancer
A. M. García-Vicente, D. Molina, J. Pérez-Beteta, M. Amo-Salas, A. Martínez-González, G. Bueno, M.J. Tello-Galán, A. Soriano-Castrejón
Annals of Nuclear Medicine 31(10) 726-735 (2017)
The prognostic value of systemic inflammatory indices in recurrent Glioma treated with bevacizumab
A. Martínez-González, C. González Díaz, R. Cabrera, M. Lloret Sáez-Bravo, P. C. Lara
Neuro-Oncology 19(suppl_3):iii76-iii77 (2017)
Towards individualized survival prediction in glioblastoma patients using machine learning methods
L. Vera, J. Pérez-Beteta, D. Molina, J. M. Borrás, M. Benavides, J. A. Barcia, C. Velásquez, D. Albillo, P. Lara, V. M. Pérez-García
Neuro-Oncology 19(3):iii84-iii84 (2017)
