The construction of locally D-optimal designs by canonical forms to an extension for the logistic model
2014 - R. Martín Martín, I. García-Camacha Gutiérrez
Applied Mathematics. 5, 824-831 (2014)
Logistic regression models for binary response problems are present in a wide variety of industrial, biological, social and medical experiments; therefore, optimum designs are a valuable tool for experimenters, leading to estimators of parameters with minimum variance. Our interest in this contribution is to provide explicit formulae for the D-optimal designs as a function of the unknown parameters for the logistic model where q is an indicator variable. We have considered an experiment based on the dose-response to a fly insecticide in which males and females respond in different ways, proposed in Atkinson et al. (1995) . To find the D-optimal designs, this problem has been reduced to a canonical form.