The Phd thesis by Alicia Martínez "Targetting hypoxia in gliomas: From mathematics to bedside" was presented on June 26, 2014. The jury included Professors José Antonio Campillo (President of the Spanish Royal Mathematical Society), Pedro Lara (President of the Spanish Radiation Oncology Society) and Andreas Deutsch (Head of the Departament for Innovative methods in Computing) from Dresden Technical University.
This thesis has explored the use of mathematical models to understand brain tumors and their microenvironment. The study is focused on gliomas and has led to the development of different types of models of differential equations that have been later used to raise novel therapeutical hypothesis. In a highly interdisciplinary collaboration with neuro-oncologists, radio-oncologists, pathologists, biologists and neuro-surgeons the model's predictions have lead to experimental work and even to the initial stages of a clinical essay.